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A flurry of activity led by ‘Pioneer of Indian bio hacking’ Dr. Sajeev Nair marks ‘World Health Day’ at Vieroots

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As a health-tech startup, World Health Day is one of the most important days for Vieroots Wellness Solutions. A young but fast-growing hub of innovation, Vieroots celebrated World Health Day with elan, especially by educating the public on the importance of taking charge of their health. Vieroots also has done deep research into Health in Covid times and found out that Covid has made 84% of people highly conscious about health and ‘Personalization of Health’ skyrocketed amidst the crisis.

The flagship Vieroots’ event of the day was a live video interaction that Vieroots Founder & Chairman Sajeev Nair had with Dr. Priti Nanda who is one of India’s leading functional medicine experts. The well-attended interaction focused on the topic – ‘Personalization is the Key to Health’.

Personalization is at the core of the healthcare mission of Sajeev Nair-led Vieroots, and Dr. Priti Nanda is not only a rare practitioner of this but an eloquent advocate. Sajeev gently probed Dr.Priti about the need for personalization, for the benefit of his viewers.

And Dr.Priti opened up not only informatively but jovially, digging into her wealth of experience in not only treating thousands of patients using the principles of functional medicine in reversing diabetes, obesity, and such lifestyle diseases but from her own experience in reversing her diabetes by a slew of measures including losing 23 kg.

Sajeev Nair allowed the fielding of a few key questions from the audience, and Dr. Priti explained further the importance of key genes like methylation genes and the detoxification genes, and how testing for them enables breakthrough interventions for reversing diabetes and obesity.

Dr. Priti then appreciated Sajeev Nair for the exemplary work he has been doing at Vieroots to further the cause of preventing diseases before they happen through Personalized Epigenetic Lifestyle Modifications. Vieroots’ EPLIMO is the first smartphone-based app in India to offer Geno-Metabolic Assessment and high-power lifestyle modifications to keep over 200 diseases at bay.

The live interaction between these two experts became highly informative for viewers as they delved into specialized antioxidants and the importance of nutrient supplementation in functional medicine. Vieroots is home to a select family of high-efficacy supplements based on time-tested Ayurvedic herbs which are validated by modern research.

Thoughtbiotics, a family of three supplements – Intuit, Focuz, & Relax – have been bestsellers at Vieroots, as they are unique with absolutely no competition in India or abroad. They work by the unique concept of restoration of the health of our Gut Microbiome and thus the Gut-Brain Axis, to promote physical wellness, concentration, memory power & sound sleep.

When Sajeev Nair finally wound up the session with Dr. Priti’s permission, viewers were left wanting for more, and the Vieroots Chairman promised his viewers that Dr. Priti Nanda would be collaborating intimately with Vierooters, especially its healthcare professionals, lifestyle consultants & customers through the Superhuman Tribe.

In other noted events from Vieroots on World Health Day 2021, the company’s Co-Founder & CEO, Aditya Narayan, conducted two very informative video interactions with two senior health professionals of the company.

The first interaction was with Dr. Biju KS, Senior Medical Officer at Vieroots. This young but uniquely experienced doctor spoke a powerful personal testimony among other things. Dr. Biju’s grandfather, father& uncles had died early due to complications of diabetes and cardiovascular diseases.

Dr. Biju too had these genetic traits and was on the verge of developing diabetes in his late 20s, but he beat it with lifestyle changes. CEO Aditya Narayan then queried Dr. Biju about why exercises should be personalized and Dr. Biju had a wealth of information to share with their viewers.

The last and final video interaction for the day was with Vieroots’ Nutritionist & Personalized Diet Consultant Manisha Manohar. CEO Aditya Narayan masterfully interacted with her for the benefit of the public to deliver some very important lessons in formulating the ideal diet.

Then he probed her about a buzzword in diets these days – the Keto Diet. Manisha Manohar had some key observations to make about the controversial Keto. From her eloquent words, viewers came to understand that Keto Diet is not the monster it is made out to be, but that it is definitely not for everyone.

For instance, those with impaired fat metabolism should never attempt the keto diet. Manisha Manohar also added that Vieroots’ core product, EPLIMO can easily find out whether one has such faulty fat metabolism. to help them decide on whether they should do keto dieting or not.

The interaction between the Vieroots CEO and their Nutritionist also shed light on how autoimmune diseases like lupus, rheumatoid arthritis, multiple sclerosis, etc can be kept at bay with EPLIMO’s lifestyle modifications.

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How the brain makes complex judgments based on context

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We frequently face difficult choices in life that are impacted by a number of variables. The orbitofrontal cortex (OFC) and the dorsal hippocampus (DH) are two key brain regions that are essential for our capacity to adjust and make sense of these unclear situations.

According to research conducted by researchers at the University of California Santa Barbara (UCSB), these regions work together to resolve ambiguity and facilitate quick learning.

Decision-making that depends on context

The results, which were released in the journal Current Biology, offer fresh perspectives on how certain brain regions assist us in navigating situations that depend on context and modifying our behavior accordingly.

According to UCSB neuroscientist Ron Keiflin, senior author, “I would argue that that’s the foundation of cognition.” That’s what prevents us from acting like mindless machines that react to stimuli in the same way every time.

“Our ability to understand that the meaning of certain stimuli is context-dependent is what gives us flexibility; it is what allows us to act in a situation-appropriate manner.”

Decision-making context

Think about choosing whether or not to answer a ringing phone. What you say depends on a number of variables, including the time of day, who might be calling, and where you are.

The “context,” which influences your choice, is made up of several components. The interaction between the OFC and DH is what gives rise to this cognitive flexibility, according to Keiflin.

Planning, reward valuation, and decision-making are linked to the OFC, which is situated directly above the eyes, whereas memory and spatial navigation depend on the DH, which is positioned deeper in the brain.

According to Keiflin, both areas contribute to a mental representation of the causal structure of the environment, or a “cognitive map.” The brain can model outcomes, forecast outcomes, and direct behavior thanks to this map.

Despite their significance, up until now there had been no systematic testing of the precise functions of these regions in contextual disambiguation, which determines how stimuli alter meaning based on context.

Contextualizing auditory stimuli

In order to find out, the researchers created an experiment in which rats were exposed to aural cues in two distinct settings: a room with bright lighting and a chamber with no light. There was a context-dependent meaning for every sound.

For instance, one sound indicated a reward (sugar water) only when it was light, and another only when it was dark.

The rats eventually learnt to link each sound to the appropriate context, and in one situation they showed that they understood by licking the reward cup in anticipation of a treat, but not in the other.

The OFC or DH was then momentarily disabled during the task by the researchers using chemogenetics. The rats’ ability to use context to predict rewards and control their behavior was lost when the OFC was turned off.

Disabling the DH, however, had minimal effect on performance, which was unexpected considering its well-established function in memory and spatial processing.

Enhanced learning from prior knowledge

For learning new context-dependent interactions, the DH proved essential, but it appeared to be unnecessary for recalling previously learned ones.

“If I walked into an advanced math lecture, I would understand – and learn – very little. But someone more mathematically knowledgeable would be able to understand the material, which would greatly facilitate learning,” Keiflin explained.

Additionally, the rats were able to pick up new relationships far more quickly after they had created a “cognitive map” of context-dependent interactions. The duration of training decreased from more than four months to a few days.

Brain areas cooperating

By employing the same chemogenetic strategy, the researchers discovered that the rats’ capacity to use past information to discover new associations was hampered when the OFC or DH were disabled.

While the DH allowed for the quick learning of novel context-dependent relationships, the OFC was crucial for using contextual knowledge to control immediate action.

This dual role emphasizes how these brain regions assist learning and decision-making in complementary ways.

Education and neuroscience Implications

According to Keiflin, neuroscience research frequently overlooks the well-established psychological and educational theories that prior information affects learning.

Knowing how the brain leverages past information to support learning could help develop educational plans and therapies for people who struggle with learning.

The study clarifies the different functions of the DH and OFC as well. In order to acquire new relationships, the DH is more important than the OFC, which aids in behavior regulation based on contextual knowledge.

These areas work together to help the brain adjust to complicated, dynamic surroundings.

Brain’s Capacity to make Decisions based on context

The study emphasizes how crucial contextual knowledge is for managing day-to-day existence. Human cognition is based on the brain’s capacity to resolve ambiguity, whether it be while choosing whether to answer a ringing phone or when adjusting to new knowledge.

This work highlights the complex processes that facilitate learning and decision-making while also advancing our knowledge of brain function by elucidating the functions of the OFC and DH.

This information creates opportunities to investigate the potential roles that disturbances in these systems may play in disorders like anxiety or problems with decision-making.

Since this type of learning is most likely far more reflective of the human learning experience, Keiflin stated that “a better neurobiological understanding of this rapid learning and inference of context-dependent relations is critical, as this form of learning is probably much more representative of the human learning experience.” 

The results open the door for future studies on the interactions between these brain areas in challenging, real-world situations, which could have implications for mental health and education.

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Nutrition and Its Role in Preventing Chronic Diseases

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Nutrition plays a pivotal role in maintaining overall health and preventing chronic diseases. The food we consume directly impacts our body’s ability to function optimally and ward off illnesses. Chronic diseases such as heart disease, diabetes, obesity, and certain types of cancer are closely linked to dietary habits. By adopting a balanced and nutritious diet, individuals can significantly reduce their risk of developing these conditions and improve their quality of life.

Understanding Chronic Diseases and Their Dietary Links

Chronic diseases are long-term health conditions that often develop gradually and persist for years. While genetics and environmental factors contribute to their onset, lifestyle choices—especially diet—play a significant role. Some key dietary factors influencing chronic disease risk include:

  • Excessive Calorie Intake: Overeating leads to obesity, which is a major risk factor for diabetes, heart disease, and certain cancers.
  • High Saturated and Trans Fat Consumption: These fats contribute to high cholesterol levels and increase the risk of cardiovascular diseases.
  • Excessive Sugar and Refined Carbohydrates: These can lead to insulin resistance and type 2 diabetes.
  • Low Fiber Intake: Insufficient dietary fiber is linked to digestive issues, high cholesterol, and increased risk of colon cancer.
  • Inadequate Micronutrients: Deficiencies in vitamins and minerals weaken the immune system and impair bodily functions.

Key Nutritional Strategies for Preventing Chronic Diseases

  1. Adopting a Balanced Diet: A well-rounded diet that includes fruits, vegetables, whole grains, lean proteins, and healthy fats provides essential nutrients and minimizes disease risk.
  2. Increasing Fiber Intake: Consuming fiber-rich foods such as whole grains, legumes, and vegetables helps regulate blood sugar levels, lower cholesterol, and improve gut health.
  3. Limiting Sugar and Processed Foods: Reducing intake of sugary drinks, snacks, and highly processed foods can prevent weight gain and lower the risk of metabolic disorders.
  4. Choosing Healthy Fats: Incorporating unsaturated fats from sources like nuts, seeds, and olive oil supports heart health while avoiding trans fats found in fried and processed foods.
  5. Maintaining Proper Hydration: Drinking enough water supports metabolic processes and helps maintain healthy weight.
  6. Monitoring Portion Sizes: Eating appropriate portions prevents overeating and helps maintain a healthy body weight.

Evidence-Based Benefits of Proper Nutrition

  1. Reduced Risk of Heart Disease: Diets rich in omega-3 fatty acids, fiber, and antioxidants help reduce cholesterol and blood pressure.
  2. Improved Glycemic Control: Balanced meals with low glycemic index foods prevent blood sugar spikes and reduce the risk of diabetes.
  3. Weight Management: Healthy eating habits help achieve and maintain an ideal weight, minimizing the risk of obesity-related diseases.
  4. Lower Cancer Risk: Antioxidants found in fruits and vegetables combat oxidative stress, reducing the risk of certain cancers.
  5. Enhanced Longevity: Nutrient-dense diets promote overall health and increase life expectancy.

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Poor Sleep During Pregnancy to Problems with the Development of the Child: Study

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According to a recent study in the Journal of Clinical Endocrinology and Metabolism, pregnant women who don’t get enough sleep are more likely to give birth to infants who have delayed neurodevelopment.

According to the study, babies born to pregnant women who slept fewer than seven hours a day on average had serious neurodevelopmental problems, with boys being especially at risk. Pregnancy-related sleep deprivation has been associated with impairments in the children’s emotional, behavioral, motor, cognitive, and language development.

Additionally, elevated C-peptide levels in the umbilical cord blood of these kids were discovered, which suggests that insulin manufacturing has changed. One result of the pancreas’ production of insulin is C-peptide.

Additionally, the study demonstrated that disorders like impaired glucose tolerance, insulin resistance, and gestational diabetes—all of which were previously linked to inadequate sleep during pregnancy—can affect a child’s neurodevelopment.

The study team clarified that maternal glucose metabolism during pregnancy may influence fetal insulin secretion, which in turn may effect neurodevelopment, even if they were unable to conclusively demonstrate that sleep deprivation actually causes neurodevelopmental abnormalities.

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