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AI that’s a “Game Changer” Finds Hidden Heart Attack Risk

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Scientists have praised technology as “game-changer” since it can identify those who are in danger of having a heart attack within the next ten years.

Using a mix of computer technology and X-rays, the artificial intelligence (AI) model is able to identify cardiac inflammation that is not visible on CT scans.

NHS England-funded five hospital trusts in Oxford, Milton Keynes, Leicester, Liverpool, and Wolverhampton are participating in a pilot study.

In a few months, an NHS decision about its use is anticipated.
Caristo Diagnostics, an Oxford University spin-off business that developed the technology, stated that it was already working on adapting it to prevent diabetes and strokes.

“This technology is transformative and game changing because for the first time we can detect the biological processes that are invisible to the human eye, which precede the development of narrowings and blockages [within the heart],” said Prof. Keith Channon, of the University of Oxford.

Patients with chest pain who are referred for a routine CT scan as part of the pilot program have the CaRi-Heart AI platform from Caristo Diagnostics analyze their scan.

The accuracy of an algorithm that identifies plaque and coronary inflammation is then confirmed by skilled operators.

Studies have indicated a connection between elevated inflammation and an increased risk of heart attacks and cardiovascular disease.

According to official statistics, the British Heart Foundation (BHF) estimates that 7.6 million people in the UK suffer from heart disease, and the yearly cost to the NHS in England is £7.4 billion.

According to the BHF, about 350,000 individuals are referred for a cardiac CT scan in the UK annually.

Eighty percent of patients in the 40,000-person Orfan research (Oxford Risk Factors and Non-invasive Imaging), which was reported in the Lancet, were returned to primary care without a clear prevention or treatment strategy.

Using that cohort as a focus, the researchers discovered that patients with coronary artery inflammation were 20–30 times more likely to die during the following ten years from a cardiac incident.

According to the BHF-funded study, 45% of the patients received medicine prescriptions or lifestyle modification recommendations as a result of the AI technology.

‘A wake-up call’

Ian Pickford is among the forty thousand patients that were involved in the research.

Following a period of severe chest pain, Ian Pickford, 58, of Barwell, Leicestershire, was referred for a CT scan in November 2023.
He was registered in the University Hospitals of Leicester NHS Trust Orfan study.

After testing utilizing the AI analysis revealed the double-glazing salesman was at risk of having a heart attack, he was advised to stop smoking, up his activity, and take statins.

Tests utilizing the AI analysis indicated the double-glazing salesman was at risk of a heart attack; as a result, he was advised to stop smoking, up his activity, and take statins.
Mr. Pickford declared, “It’s a huge wake-up call.”


“And when you see it on paper, you realise how serious it is. It’s something you can look at each day and think, ‘I’ve got to do something about this’.”

Based on the amount of fat around the arteries, the AI model calculates heart inflammation.

The Orfan study head, Prof. Charalambos Antoniades, claimed that the instruments up until this point were antiquated as risk calculators could only evaluate broad risk variables, including a patient’s obesity, diabetes, or smoking habit.

“Now, we know exactly which patient has the disease activity in their arteries before the disease has even developed,” he stated, referring to the type of AI technology available.

“This means we can move early to end the disease process and treat this patient to prevent the disease from developing and then prevent heart attacks from happening.”

The technology is presently being evaluated by the National Institute for Health and Care Excellence to see if it should be implemented throughout the National Health Service.

Approved for usage in Europe and Australia, it is currently undergoing assessment in the United States as well.

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An SEO startup has raised $850,000 to assist businesses in utilizing AI-powered search

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Pre-seed finance totaling $850,000 has been received by Ecomtent, an AI start-up that assists retailers and sellers in getting ready for the AI-driven e-commerce search of the future. The investment was spearheaded by MaRS Investment Accelerator Fund (IAF) and included senior leadership from the tech sector, Techstars x eBay Ventures, and C-Suite Angels from Retailers.

Ecoment is going to completely change how merchants and sellers are ready for a world where searches are based on LLM. Ecomtent was founded in 2022 by Timur Luguev, a PhD & Postdoctoral Researcher in Machine Learning, and Max Sinclair, who worked for six years at Amazon on strategic initiatives such as the launch of Amazon in Singapore and the EU’s first grocery store. Ecomtent’s technology allows sellers and retailers to create written and visual content that is specifically optimized for AI-powered search across large catalogues at scale, eliminating bottlenecks on internal content teams and outside agencies and saving weeks of labor.

CEO Sinclair predicted a “Ecommerce is about to change fundamentally,” in e-commerce. “Generative AI will completely transform how consumers shop online, with conversational-style search poised to become the new normal. The current best SEO practices will look completely outdated in just 12 months. Longtail keyword matching is dead, and the future will be matching customer intent across both written and visual assets.”

With two major retailers having annual revenues of $11 billion and $14 billion, respectively, the company has already completed successful pilots with both, demonstrating considerable market progress. These successes have made Ecomtent a popular choice among Amazon Seller and Amazon Agency communities, allowing these clients to produce infographics, optimized content, A+ Content, and high-quality lifestyle photos at scale. With a recent submission approved by the USPTO, its patent-pending technology has demonstrated that AI-generated content may raise product listing conversion rates by as much as 30%.

“I have been incredibly impressed with Ecomtent’s technology, which has augmented our internal content team’s speed and scale to be 10x more productive,” stated Vincenzo Toscano, CEO of Full-Service Amazon and Walmart Agency Ecomcy. A key component of succeeding in e-commerce is having the appropriate software tools in your toolbox, according to Ben Leonard, a seven-figure Amazon seller and best-selling author of Quit Stalling and Build Your Brand. Beyond simply being the product listing tool of the future, ecomtent currently outperforms its closest, more established competitors in terms of results.

With the help of this most recent fundraising round, Ecomtent will be able to develop faster, hire more people, improve its AI capabilities, and extend its operations in order to satisfy the increasing demand from companies figuring out how to use AI-powered search. According to Emil Savov, Managing Director of MaRS IAF, “We are excited by the unique composition of Ecomtent’s founding team, and the specialist AI talent from elite institutions they have recruited around them, to capitalize on this moment of incredible opportunity to build a category-defining business.”

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Singaporean Venture Capital Raises Startup Debt Fund Despite Low Valuations

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Private lender Genesis Alternative Startups, which supports startups and growth-stage businesses, closed its second loan fund below target because foreign investors are still wary of Southeast Asia’s startup scene.

The Singaporean company secured additional investors, such as Israel’s OurCrowd Ltd. and Japan’s Mizuho Bank, to raise $125 million for the fund, which will support startup businesses throughout Southeast Asia. The fund took almost two years to close, having sought between $120 and $180 million.

Private lender Genesis Alternative startups, which supports startups and growth-stage businesses, closed its second loan fund below target because foreign investors are still wary of Southeast Asia’s startup scene.

The Singaporean company secured additional investors, such as Israel’s OurCrowd Ltd. and Japan’s Mizuho Bank, to raise $125 million for the fund, which will support startup businesses throughout Southeast Asia. The fund took almost two years to close, having sought between $120 and $180 million.

In recent quarters, there has been an increasing interest in venture lending, or loans given to startups, as more businesses choose to use the debt market rather than raise equity. The values of computer businesses have been severely damaged by a bleak prognosis for the global economy, and venture capital firms have been finding it difficult to raise money in the midst of a sluggish market for IPOs. Nevertheless, because many of its still-unprofitable businesses are seen as high-risk by global venture capitalists, Southeast Asia continues to be a difficult market for raising both financing and equity.

“It’s never easy to raise funds, and it’s been more difficult in this environment,” Genesis managing partner and co-founder Jeremy Loh stated in an interview. “This is a period of time where founders must be able to demonstrate that they can grow at a sustainable pace without relying on too much equity.”

Aozora Bank Ltd., Korea Development Bank, and Silverhorn Group were among the more than 80% of investors in Genesis’s inaugural fund who also made investments in its most recent fund.

Nine firms, including Aonic, Eezee Pte, and Akulaku Inc., have already received more than $20 million in loans from the second fund, according to Loh. Because businesses lack collateral or aren’t yet profitable, entrepreneurs that don’t often qualify for standard bank loans are given credit by Genesis. In Southeast Asia, the company’s initial $90 million fund has supported 25 firms, ranging from Series A to pre-IPO. Among its portfolio firms are the online lender Akulaku, located in Jakarta, and the buy-now, pay-later startup Pace.Singaporean Venture Capital Raises Startup Debt Fund Despite Low Valuations

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Ilya Sutskever, a Co-Founder of OpenAI, Raises $1 Billion for his New AI Company

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Ilya Sutskever, a co-founder of OpenAI who departed the artificial intelligence startup in May, has raised $1 billion for his new venture, Safe Superintelligence, or SSI, from investors.

In a post on X, the company disclosed that investors included SV Angel, DST Global, Sequoia Capital, Andreessen Horowitz, and NFDG, an investment partnership co-managed by SSI executive Daniel Gross.

In May, Sutskever announced the new endeavor on X, writing, “We will pursue safe superintelligence in a straight shot, with one focus, one goal, and one product.”

Chief scientist Sutskever co-led the Superalignment team at OpenAI with Jan Leike, who departed in May to work for competitor artificial intelligence company Anthropic. Only a year after announcing the group, OpenAI dissolved the team shortly after their departures.

At the time, Leike stated that OpenAI’s “safety culture and processes have taken a backseat to shiny products” in a post on X.

Along with Daniel Levy, a former employee of OpenAI, and Daniel Gross, who handled Apple’s AI and search initiatives, Sutskever founded SSI. The business maintains offices in Tel Aviv, Israel, and Palo Alto, California.

The corporation wrote on X, “SSI is our mission, our name, and our entire product roadmap, because it is our sole focus.” “Our singular focus means no distraction by management overhead or product cycles, and our business model means safety, security, and progress are all insulated from short-term commercial pressures.”

Sam Altman, the CEO and co-founder of OpenAI, was temporarily removed in November, with Sutskever being one of the board members engaged.

In November, Altman was not “consistently candid in his communications with the board,” according to a statement released by OpenAI’s board. Things looked more complicated very quickly. As reported by the Wall Street Journal and other media, Altman and Sutskever were more keen to advance the delivery of new technology, while Sutskever focused on making sure that artificial intelligence would not damage people.

An open letter indicating their intention to quit in response to the board’s decision was signed by nearly every employee of OpenAI. After a few days, Altman returned to the organization.

Sutskever apologized to the public for his part in the ordeal after Altman’s abrupt dismissal and before his prompt reinstatement.

On November 20, Sutskever posted on X, saying, “I deeply regret my participation in the board’s actions.” “I never intended to harm OpenAI. I love everything we’ve built together and I will do everything I can to reunite the company.”Ilya Sutskever, a co-founder of OpenAI, raises $1 billion for his new AI company

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