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Google’s Isomorphic Labs Unveils AlphaFold 3, AI that Predicts Structures of Life’s Molecules

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The Google and DeepMind subsidiary Isomorphic Labs has created a new artificial intelligence model that is purportedly more accurate than existing methods at predicting the configurations and interactions of every molecule in life.

The AlphaFold 3 system, according to co-founder of DeepMind Demis Hassabis, “can predict the structures and interactions of nearly all of life’s molecules with state-of-the-art accuracy including proteins, DNA, and RNA.”

Protein interactions are essential for drug discovery and development. Examples of these interactions include those between enzymes that are essential for human metabolism and antibodies that fight infectious illnesses.

Published on May 8 in the academic journal Nature, DeepMind said that the findings might drastically cut down on the time and expense needed to create medicines that have the potential to save lives.

“We can design a molecule that will bind to a specific place on a protein, and we can predict how strongly it will bind,” Hassabis stated in a press release, utilizing these new powers.

Earlier, AlphaFold revolutionized research by making protein 3D structure prediction more straightforward. Nevertheless, prior to AlphaFold 3’s improvement, it was unable to forecast situations in which a protein bound with another molecule.

Despite being limited to non-commercial use, scientists are reportedly excited about its increased predictive power and ability to speed up the drug discovery process.

“AlphaFold 3 allows us to generate very precise structural predictions in a matter of seconds, according to a statement released by Isomorphic Labs on X.”

“This discovery opens up exciting possibilities for drug discovery, allowing us to rationally develop therapeutics against targets that were previously difficult or deemed intractable to modulate,” the blog post continued.

The AlphaFold Server Login Process

The AlphaFold Server, a recently released research tool, will be available to scientists for free, according to a statement made by Google DeepMind and Isomorphic Labs.

Isomorphic Labs is apparently collaborating with pharmaceutical companies to use the potential of AlphaFold 3 in drug design. The goal is to tackle practical drug design issues and ultimately create novel, game-changing medicines for patients.

Since 2021, a database containing more than 200 million protein structures has made AlphaFold’s predictions freely available to non-commercial researchers. In academic works, this resource has been mentioned thousands of times.

According to DeepMind, researchers may now conduct experiments with just a few clicks thanks to the new server’s simplified workflow.

Using a FASTA file, AlphaFold Server’s web interface will enable data entry for a variety of biological molecule types. After processing the task, the AI model displays a 3D overview of the structure.

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Threads uses a more sophisticated search to compete with Bluesky

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Instagram Threads, a rival to Meta’s X, will have an enhanced search experience, the firm said Monday. The app, which is based on Instagram’s social graph and provides a Meta-run substitute for Elon Musk’s X, is introducing a new feature that lets users search for certain posts by date ranges and user profiles.

Compared to X’s advanced search, which now allows users to refine queries by language, keywords, exact phrases, excluded terms, hashtags, and more, this is less thorough. However, it does make it simpler for users of Threads to find particular messages. Additionally, it will make Threads’ search more comparable to Bluesky’s, which also lets users use sophisticated queries to restrict searches by user profiles, date ranges, and other criteria. However, not all of the filtering options are yet visible in the Bluesky app’s user interface.

In order to counter the danger posed by social networking startup Bluesky, which has quickly gained traction as another X competitor, Meta has started launching new features in quick succession in recent days. Bluesky had more than 9 million users in September, but in the weeks after the U.S. elections, users left X due to Elon Musk’s political views and other policy changes, including plans to alter the way blocks operate and let AI companies train on X user data. According to Bluesky, there are currently around 24 million users.

Meta’s Threads introduced new features to counter Bluesky’s potential, such as an improved algorithm, a design modification that makes switching between feeds easier, and the option for users to select their own default feed. Additionally, it was observed creating Starter Packs, its own version of Bluesky’s user-curated recommendation lists.

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Apple’s own 5G modem-equipped iPhone SE 4 is “confirmed” to launch in March

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Tom O’Malley, an analyst at Barclays, recently visited Asia with his colleagues to speak with suppliers and makers of electronics. The analysts said they had “confirmed” that a fourth-generation iPhone SE with an Apple-designed 5G modem is scheduled to launch near the end of the first quarter next year in a research note they released this week that outlines the main conclusions from the trip. That timeline implies that the next iPhone SE will be unveiled in March, similar to when the present model was unveiled in 2022, in keeping with earlier rumors.

The rumored features of the fourth-generation iPhone SE include a 6.1-inch OLED display, Face ID, a newer A-series chip, a USB-C port, a single 48-megapixel rear camera, 8GB of RAM to enable Apple Intelligence support, and the previously mentioned Apple-designed 5G modem. The SE is anticipated to have a similar design to the base iPhone 14.

Since 2018, Apple is said to have been developing its own 5G modem for iPhones, a move that will let it lessen and eventually do away with its reliance on Qualcomm. With Qualcomm’s 5G modem supply arrangement for iPhone launches extended through 2026 earlier this year, Apple still has plenty of time to finish switching to its own modem. In addition to the fourth-generation iPhone SE, Apple analyst Ming-Chi Kuo earlier stated that the so-called “iPhone 17 Air” would come with a 5G modem that was created by Apple.

Whether Apple’s initial 5G modem would offer any advantages to consumers over Qualcomm’s modems, such quicker speeds, is uncertain.

Qualcomm was sued by Apple in 2017 for anticompetitive behavior and $1 billion in unpaid royalties. In 2019, Apple purchased the majority of Intel’s smartphone modem business after the two firms reached a settlement in the dispute. Apple was able to support its development by acquiring a portfolio of patents relating to cellular technology. It appears that we will eventually be able to enjoy the results of our effort in four more months.

On March 8, 2022, Apple made the announcement of the third-generation iPhone SE online. With antiquated features like a Touch ID button, a Lightning port, and large bezels surrounding the screen, the handset resembles the iPhone 8. The iPhone SE presently retails for $429 in the United States, but the new model may see a price increase of at least a little.

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Google is said to be discontinuing the Pixel Tablet 2 and may be leaving the market once more

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Google terminated the development of the Pixel Tablet 3 yesterday, according to Android Headlines, even before a second-generation model was announced. The second-generation Pixel Tablet has actually been canceled, according to the report. This means that the gadget that was released last year will likely be a one-off, and Google is abandoning the tablet market for the second time in just over five years.

If accurate, the report indicates that Google has determined that it is not worth investing more money in a follow-up because of the dismal sales of the Pixel Tablet. Rumors of a keyboard accessory and more functionality for the now-defunct project surfaced as recently as last week.

It’s important to keep in mind that Google’s Nest subsidiary may abandon its plans for large-screen products in favor of developing technologies like the Nest Hub and Hub Max rather than standalone tablets.

Google has always had difficulty making a significant impact in the tablet market and creating a competitor that can match Apple’s iPad in terms of sales and general performance, not helped in the least by its inconsistent approach. Even though the hardware was good, it never really fought back after getting off to a promising start with the Nexus 7 eons ago. Another problem that has hampered Google’s efforts is that Android significantly trails iPadOS in terms of the quantity of third-party apps that are tablet-optimized.

After the Pixel Slate received tremendously unfavorable reviews, the firm first declared that it was finished producing tablets in 2019. Two tablets that were still in development at the time were discarded.

By 2022, however, Google had altered its mind and declared that a tablet was being developed by its Pixel hardware team. The $499 Pixel Tablet was the final version of the gadget, which came with a speaker dock that the tablet could magnetically connect to. (Google would subsequently charge $399 for the tablet alone.)

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